The precision of the Accu-chek Advantage, Onetouch Horizon and Sensocard for blood glucose monitoring from about 3.1-33.3 mmol L-1 is good. In terms of rating, while all the glucose meters gave precisions at about the same level (i.e., 1.0), Onetouch Horizon is generating the closest value to the reference method with a difference between mean of -0.06, followed by Sensocard of 0.19 and Accu-chek Advantage with a value of -0.55. Sensocard could under-estimate with a bias of 0.2. Bland-Altman analysis indicates that Onetouch Horizon and Accu-chek Advantage have the tendency of overestimating blood glucose with a bias of -0.1 and -0.5, respectively. The mean value generated by the WHO reference method (7.91☐.35) was not significantly different (p = 0.2816) from that produced by the Accu-chek Advantage (8.46☐.36), Sensocard (7.72☐.35 p = 0.7028) and Onetouch Horizon (7.97☐.35 p = 0.9044). At the same time venous blood glucose was analyzed using the WHO reference Glucose Oxidase Method (GOD).
The blood glucose levels were analyzed on glucose meters Accu-chek Advantage, Sensocard and Onetouch Horizon by finger stick, using amperometry Technology. One hundred and ninety consenting subjects were included in the study. The study was conducted from January to March, 2009 at the Komfo Anokye Teaching Hospital, Kumasi. This study evaluated the accuracy and precision associated with the use of three popular alternative-site blood glucose monitors, Accu-chek Advantage, Onetouch Horizon and Sensocard, using forearm venous blood samples and capillary blood samples. Precision And Accuracy Of Three Blood Glucose Meters: Accu-chek Advantage, One Touch Horizon And Sensocard Experiments in animal models are critical to investigate the significances of the physiologica Glucometers are used for strict self-monitoring of blood glucose levels (SMBG) by the patients themselves in intensive diabetes treatment.
Blood glucose levels measured by laboratory biochemical testing are used for the diagnosis of diabetes and for therapeutic monitoring of diabetic patients1,2. Blood glucose is an essential parameter in the study of metabolism and diabetes. Our data suggest that the blood glucose levels measured by glucometers in mice tended to be higher than the plasma glucose levels yielded by the biochemical test under the hyperglycemic state, and that differences in the measured levels were observed according to the blood collection method depending on the glycemia status. Most glucometers recorded higher blood glucose levels after glucose loading and lower blood glucose levels after insulin loading in retro-orbital sinus blood as compared to tail vein blood. In both blood samples obtained by retro-orbital sinus puncture and those obtained by tail-tip amputation, 10 of the 11 models of glucometers yielded higher glucose values, while 1 yielded lower glucose values, than the plasma glucose values yielded by the laboratory test, the differences being in direct proportion to the plasma glucose values. In this study, we evaluated the consistency between the blood glucose levels measured by 11 models of glucometers and plasma glucose levels measured by a laboratory biochemical test in blood samples collected by retro-orbital sinus puncture or tail-tip amputation. However, the appropriateness of measuring blood glucose levels using glucometers in animal models remains unclear.
Glucometers are also widely used in diabetes research conducted using animal models. Evaluation Of The Appropriateness Of Using Glucometers For Measuring The Blood Glucose Levels In Mice